At least 15 IPOs are expected to price this week, including six biotechs, a government contractor and a Russian job siteThe U.S. initial public offering market is facing its biggest week since 2015, with at least 15 deals expected to be priced, including that of Uber, the biggest IPO since Alibaba BABA, -0.97% in 2014 and the biggest U.S. company deal since Facebook FB, +0.06% in 2012. Uber UBER, +0.00% is expected to price its much anticipated offering on Thursday, just weeks after its ride-sharing rival Lyft Inc. LYFT, -6.37% , which has had a rocky start as a public company. Lyft’s shares have fallen 15% from their IPO price, given widespread concerns about the company’s ability to become profitable. Lyft will report its first earnings since going public on Tuesday after the bell and potential Uber investors will likely pay close attention. To be sure, the two companies have different business models, with Lyft strongly focused on the U.S., while Uber has global ambitions that extend to food delivery, freight and even health care. “Uber’s IPO tests the extent of Silicon Valley’s philosophy of growth at all costs,” according to Renaissance Capital, a provider of institutional research and IPO exchange-traded funds. Lyft’s numbers are not the only event expected to influence the Uber IPO. Uber and Lyft drivers are planning a strike from 7 a.m. to 9 a.m. on Wednesday to protest their wages, their treatment as independent contractors rather than employees, and the lack of regulation governing the new sector. Drivers have repeatedly challenged the ride-sharing companies for refusing to deem them employees, which means they are responsible for maintenance of their own vehicles as well as gas and insurance, which greatly reduces the amount they can earn per hour. Wedbush analyst Daniel Ives said take rates, the amount the companies deduct from fares, will remain the hot-button issue for Uber and Lyft. Investors were surprised to discover Uber’s take rate of 22%, as disclosed in its IPO documents, which is well below expectations in the 30% range, said Ives. “We do see added risk from Uber aiming to take greater share of the fare from drivers and expect that the more Uber pushes here, the more drivers will fight back and protest, increasing the likelihood of regulations (particularly at the state level in the U.S. and in Europe) of minimum wage guarantees,” Ives wrote in a Monday note. Analysts have been comparing the two competitors ahead of the Uber deal, as MarketWatch’s Emily Bary reported. Wedbush’s Ygal Arounian recently declared his preference for Uber because its robust platform and logistics expertise reminded him of a younger Amazon.com Inc. Ives also favors Uber over Lyft “at current levels.” D.A. Davidson’s Tom White remains on the sideline for Uber due to the company’s deteriorating margins and slowing revenue growth, but he still rates Lyft shares a buy. But both companies have big operating losses — Uber’s came to $3.03 billion for 2018 — and there is no clear path to profitability in sight. “With about $50 billion in gross bookings and $11 billion in revenue, Uber can only justify its $86 billion market cap by scaling its global offering further and then dialing up its take rate (roughly 20%),” said Renaissance. Investors might want to view it as a venture capital bet and think more about where it might be in 10 years time, assuming it hasn’t run out of cash by then, the company said in commentary. And then the rest Aside from Uber, the week will include deals from six biotech companies, a government contractor, an industrial engineering company, a Texas bank, a post office REIT, a Russian job site, a rugged phone maker and two blank check companies, according to Renaissance. The second biggest deal on tap is from Virginia-based Parsons Corp., a defense technology company that is aiming to raise $500 million. Parsons is owned by its more than 15,000 employees through an employee stock ownership plan, or ESOP. The ESOP took it private back in 1984. Proceeds of that deal will be used to pay an IPO dividend and to repay debt. One other ESOP on deck this week is Wisconsin-based Mayville Engineering, which makes parts for commercial and industrial vehicles. That company is planning to raise up to $131 million by selling 6.3 million shares priced at $19 to $21 each. Proceeds will be used to repay debt and for general corporate purposes, including potential future acquisitions. HeadHunter Group HHR, +0.00% , an online job recruitment company from Russia, is expected to raise up to $220 million by offering 16.3 million shares priced at $11 to $13.50 each. From the biotech sector come deals from Applied Therapeutics APLT, +0.00% , which is developing therapies for diabetic cardiomyopathy, a disorder of the heart muscle in patients with diabetes; Axcella Health AXLA, +0.00% , which is developing therapies to treat metabolic dysregulation in the liver; Cortexyme CRTX, +0.00% , which is developing a therapy for Alzheimer’s disease; Milestone Pharmaceuticals MIST, +0.00% , a Canadian biotech that is developing treatments for heart-rate conditions; NextCure NXTC, +0.00% , a clinical-stage biotech working on next-generation cancer immunotherapies; and Trevi Therapeutics TRVI, +0.25% , which is developing an extended-release opioid for new indications. West Texas commercial bank South Plains Financial SPFI, +0.00% is expecting to raise up to $66 million, while Postal Realty Trust PSTL, +0.00% is expected to raise up to $105 million. SonimTechnologies SONM, +0.00% a San Mateo, Calif.–based maker of rugged mobile phones is expected to raise up to $54 million. Health Sciences Acquisition HSACU, +0.00% , a blank-check company that aims to acquire a biopharma or medical-technology company, is expected to raise up to $100 million, while Landcadia Holdings II LCAHU, +0.10% , a blank-check company that aims to acquire an entertainment business, is expected to raise up to $250 million. The Renaissance IPO exchange-traded fund IPO, -0.49% has gained 35% in 2019 so far, while the Renaissance International IPO ETF IPOS, +0.00% has gained 15%. The Dow Jones Industrial Average DJIA, +0.10% has gained 13% and the S&P 500 SPX, +0.09% has gained 16%.